* Referenzen klinische Studien:

• Wang J. et al., “Efficacy of buffered hypertonic seawater in different phenotypes of chronic rhinosinusitis with nasal polyps after endoscopic sinus surgery: A randomized double-blind study”, Am. J. Otolaryngol, vol. 41, pp. 1–8, 2020.
• Culig J. et al., “Efficiency of hypertonic and isotonic seawater solutions in chronic rhinosinusitis”, Med. Glas., vol. 7, no. 2, pp. 116–123, 2010.
• Friedman M. et al., “Dead Sea Salt irrigations vs saline irrigations with nasal steroids for symptomatic treatment of chronic rhinosinusitis: A randomized, prospective double-blind study”, Int. Forum. Allergy Rhinol., vol. 2, pp. 252–257, 2012.
• Koksal T. et al., “Comparison between the use of saline and seawater for nasal obstruction in children under 2 years of age with acute upper respiratory infection”, Turk. J. Med. Sci., vol. 46, pp. 1004–1013, 2016.
• Singh R. et al., “Comparative study of intranasal hypertonic”, Int. J; Otorhinolaryngol. Head Neck Surg., vol. 3, no. 1, pp. 104–107, 2017.
• Strnad P. et al., “Efficacy of nasal irrigation with 2.2% hypertonic seawater in the treatment of chronic rhinosinusitis in adults”, Rev. Laryngol. Otol. Rhinol., vol. 137, no. 1, pp. 3–10, 2016.
• Rapiejko P et al., “The use of a hypertonic sea water solution in patients after surgical treatment of the nose and paranasal sinuses”, Otolaryngol. Pol., vol. 64, no. 1, pp. 20–30, 2010.